Cellular therapy for sickle cell disease
نویسندگان
چکیده
منابع مشابه
Neonatal Screening for Sickle Cell Disease in Southwest Iran
the risk of sickle cell complications that is a common hemoglobin disorder in Southwest Iran. This study aimed at determining the incidence of Sickle Cell Disease (SCD) and other Hemoglobinopathies in newborn being at risk based on ethnic origin. Materials and Methods: In this descriptive epidemiologic study, between September 2013 and September 2015, 8363 newborn blood samples were test...
متن کاملIntracardiac Thrombosis in Sickle Cell Disease
In patients with sickle cell disease, thrombotic microangiopathy is a rare complication. Also in sickle cell disease, intracardiac thrombus formation without structural heart diseases or atrial arrhythmias is a rare phenomenon. We herein describe a 22-year-old woman, who was a known case of sickle cell-βthalassemia, had a history of recent missed abortion, and was admitted with a vaso-occlusive...
متن کاملCurrent therapy of sickle cell disease.
H omozygous sickle cell disease (SCD) is an auto-somal recessive genetic disease that results from the substitution of valine for glutamic acid at position 6 of the β-globin gene, leading to production of a defective form of hemoglobin, hemoglo-bin S (HbS). The prevalence of SCD is about 1-2% among African descendants in Europe and the United States and 4% or higher in West Africa. SCD shows br...
متن کاملTransfusion therapy for sickle cell disease: a balancing act.
Transfusion therapy is a key intervention in decreasing morbidity and mortality in patients with sickle cell disease (SCD). Current indications for acute and chronic transfusion therapy have significantly increased the number of RBC units transfused to patients with SCD worldwide. This review summarizes transfusion management for the treatment or prevention of neurologic and perioperative compl...
متن کاملNeonatal Screening for Sickle Cell Disease in South West Iran: a Pilot Study
Background: Children affected with sickle cell disease (SCD) are at increased risk for severe morbidity and mortality, especially during the first 3-5 years of life. It is suggested that early treatment can improve the condition. The aim of this pilot study was to estimate the incidence of hemoglobin S (HbS) by umbilical cord blood screening in Khorramshahr and Abadan cities in southwest of Ira...
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ژورنال
عنوان ژورنال: Cytotherapy
سال: 2016
ISSN: 1465-3249
DOI: 10.1016/j.jcyt.2016.06.011